This blood test is used to measure leptin levels. It is well documented that an association exists between leptin levels and inflammation. Leptin is a hormone that is produced in several areas of the body to include white and brown adipose tissue (fat), ovaries, breasts, skeletal muscle, stomach, mammary epithelial cells, bone marrow, liver, pituitary gland and placenta.

The amount of leptin in the body is proportionate to the amount of fat in the body and plays a major role in fat metabolism. Leptin was originally thought to be a signal to lose weight, but it may instead be a signal to the hypothalamus (part of the brain affected by Alzheimer’s disease) to suppress the appetite. Researchers are currently exploring the possibility that leptin levels may be an indicator of energy balance. Though controversial at this time, some scientists believe there is a correlation between the production of melatonin and leptin. It has been suggested that melatonin may down regulate the production of leptin, thereby acting as a natural appetite suppressant during sleep.

Test Preparation For Optimal Results:

If possible, have the lab collected early in the morning or shortly after waking. Do not take supplements on the day of the test. For comparison purposes, have subsequent labs collected close to the same time.

Disclaimer: Your health care provider should evaluate a deviation from normal ranges.