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GLP -3 Organic Acid Test+Metals Hair+IgG Dried Blood Spot$775.00 Add to cart
GLP -3 Organic Acid Test+Metals Hair+IgG Dried Blood Spot
Testing for organic acids, IgG’s, food allergies and metals is crucial to detect any malfunctioning within the body.
This innovative and valuable panel offers testing for organic acids, IgG’s, food allergies and metals is crucial to detect any malfunctioning within the body. This test panel may be used for:
• Evaluate energy production.
• Assess central nervous system function.
• Evaluate the integrity of the intestinal wall.
• Reveal high levels of GI yeast and bacteria.
• Detect nutritional & antioxidant deficiencies.
• Evaluate fatty acid metabolism.
• Identify excess oxalate.
• Identifies possible food reactions that may be contributing to physical or mental symptoms.
• Determine if metal toxicity or mineral deficiency is contributing to a disorder.
• Monitor the elimination of heavy metals from the body.
Urine: 10 mL of first-morning urine before food or drink is suggested. For optimal results, avoid apples, grapes (including raisins), pears, cranberries and their juices 24 hours prior to specimen collection.
Dried Blood Spot (DBS): Five full circles of dried blood on the protein saver card is required. Hair: 0.25 grams (approximately 1 tablespoon) of hair is the absolute minimum. 1 gram is preferred.
Note: The elimination of a food will reduce the ability for our laboratory to detect antibodies (allergies) to that food.$775.00
Glyphosate Testing (Urine) – Great Plains Laboratory$99.00 Add to cart
Glyphosate Testing (Urine) – Great Plains Laboratory
Online Lab testing for Glyphosate is now available. Glyphosate is the world’s most widely produced herbicide and is the primary toxic chemical in Roundup™, as well as in many other herbicides. In addition, it is a broad-spectrum herbicide that is used in more than 700 different products from agriculture and forestry to home use. Glyphosate was introduced in the 1970s to kill weeds by targeting the enzymes that produce the amino acids tyrosine, tryptophan, and phenylalanine. The enzymes of many bacteria are also susceptible to inhibition by this chemical, thus altering the flora of many animals.$99.00
GPL-TOX: Toxic Non-Metal Chemical Profile General$250.00 Add to cart
IgG Food Allergy Test with Candida (Blood Spot Test)$250.00 Add to cart
IgG Food Allergy Test with Candida (Blood Spot Test)
ASSESSES 190 FOODS Including Hemp as a Food Source as Medical CBD
Includes a wide range of foods, common in the Western, Asian, and Mediterranean diets. We have added a hemp allergy marker because it is very common now as a food source or as medical CBD. We are able to run the IgG Food MAP on both serum and dried blood spot samples.
SUPERIOR SENSITIVITY AND ACCURACY COMPARED TO ELISA
GPL’s xMAP® immunoassay with fluorescence readout has proven to be even more sensitive than ELISA tests. The IgG Food MAP test detects all food antibodies with greater precision than ELISA tests thanks to the superior technology we’ve developed for the test.
Antigen-specific IgG antibodies are captured on multiplexed magnetic beads, using xMAP® (Multiple Analyte Profiling) technology. The xMAP® bead-based immunoassay allows for the simultaneous detection of IgG antibodies to all 190 foods in two single test wells, reducing sample volume requirements and reagents while increasing sensitivity and specificity as compared to traditional plate-based ELISA tests. The upgraded immunoassay is cost and time effective, easy to perform and reproducible. We have now fully automated all steps of our testing processes, leading to even better precision.
GREATER RELIABILITY OF RESULTS
In the multiplexed bead-based immunoassay, food antigenic proteins are first covalently bound to beads. The beads are mixed with the patient’s sample where bead-bound antigens capture the specific IgG antibodies present in the sample. The food-specific IgG antibody level of each sample is detected with a fluorescent-labeled antibody against IgG. Every reaction with a patient sample also contains control beads to ensure accurate results. The fluorescent signal is measured using an xMAP® analyzer. The amount of food-specific antibody detected per allergen specific bead is directly proportional to the fluorescent signals. The higher the fluorescence, the more specific IgG antibodies are present in the sample. Once test results are available for review, our Quality Assurance (QA) team carefully verifies that quality control measures are within instrument and assay specifications.
TESTS FOR SPECIFIC FOOD ANTIGENIC PROTEINS
Detection to multiple analyte detection. The multiplexed, bead-based assay only detects IgGs against food antigenic proteins that were covalently bound to the beads, making this assay more specific to proteins than the ELISA. In the ELISA, there is no covalent binding of proteins; instead, proteins or other antigens are bound to the surface of a plastic well by adsorption. This non-specificity of the surface allows the binding of glycan-rich molecules such as Candida and yeast. Because of this, GPL is providing a separate report for the yeasts which will be tested by ELISA, rather than the xMAP® immunoassay.
WHAT IS IGG?
IgG is the major antibody found in serum. IgGs are composed of two fragment antigen binding (Fab) regions that contain the antigen binding sites and the Fc region, which is responsible for most of the biologic activity of the antibodies (Figure 1). An antigen is a substance that causes the immune system to produce an antibody that specifically reacts with it. IgG-mediated reactions to food antigens may be delayed by several hours or days, whereas IgE food antibody reactions are quite immediate.
Human IgG is separated into four subclasses denoted IgG1, IgG2, IgG3, and IgG4. Each subclass varies in abundance and biological function. IgG1 and IgG3 are predominantly responsible for antibody protection against reinfection. IgG2 antibodies are opsonic (marking a pathogen for ingestion and destruction) and develop in response to carbohydrate polysaccharide antigens. IgG4 molecules function as skin-sensitizing immunoglobulins and are thought to block antibodies produced in response to chronic exposure to antigens.$250.00