Cyrex Array 2: Intestinal Antigenic Permeability Screen
Purpose:
This panel evaluates the integrity of the intestinal tight junctions—commonly referred to as “leaky gut.” It measures immune responses to multiple components of the gut barrier, including zonulin, actomyosin, and occludin.
Why It Matters:
A compromised gut barrier allows undigested food particles, toxins, and microbes to escape into the bloodstream, triggering immune responses that can fuel systemic inflammation and contribute to autoimmune disease. Array 2 identifies whether the intestinal permeability is transcellular, paracellular, or both.
Key Insights:
- Helps detect early signs of intestinal permeability
- Guides targeted interventions to restore gut integrity
- Essential for autoimmune prevention and management
Cyrex Array 20: Multiple Food Immune Reactivity Screen
Purpose:
Is Your Brain Barrier Protecting You?
The Cyrex Array 20 Blood-Brain Barrier (BBB) Permeability Test is an advanced clinical immunology test designed to assess the integrity of your blood-brain barrier — the critical shield that protects your brain from harmful substances, toxins, and pathogens. If this barrier becomes compromised, or “leaky,” unwanted molecules can enter the brain, triggering neuroinflammation and potentially contributing to serious neurological conditions.
What Does the Cyrex Array 20 Test Measure?
This innovative blood test measures IgG, IgA, and IgM antibodies against two major blood-brain barrier proteins — S100B and Claudin-5 — which are key markers of BBB integrity. Elevated antibodies to these proteins can signal a breach in the barrier caused by stress, trauma, gut bacterial toxins, food sensitivities, environmental chemicals, or pathogens.
Who Should Consider This Test?
The Cyrex Array 20 may be right for you if you experience:
- Persistent brain fog, poor concentration, or memory lapses
- Unexplained headaches or migraines
- Chronic fatigue that doesn’t improve with rest
- Mood swings, anxiety, or depression unresponsive to standard treatments
- Balance or coordination problems
- Neurological symptoms associated with autoimmune conditions
- Symptoms following a traumatic brain injury (TBI) or contact sport activity
- Gut issues like leaky gut that may be affecting brain function
Cyrex Array 22: Chemical Immune Reactivity Screen
Purpose:
This unique test screens for immune reactivity to over 40 common chemicals, including formaldehyde, BPA, parabens, benzene, glyphosate, and more—many of which are known endocrine disruptors and mitochondrial toxins.
Why It Matters:
In today’s world, we’re exposed to a variety of environmental chemicals that can contribute to immune dysregulation and chronic disease. Array 22 evaluates whether your immune system is reacting to these toxins, which may exacerbate inflammation, autoimmune flares, and fatigue.
Key Insights:
- Identifies immune responses to commonly encountered environmental toxins
- Supports detoxification planning and environmental avoidance
- Invaluable for patients with chronic fatigue, autoimmunity, or multiple chemical sensitivity
Why Consider All Three Arrays Together?
Together, Cyrex Arrays 2, 20, and 22 provide a comprehensive map of barrier dysfunction, food immune reactivity, and environmental chemical burden—three critical contributors to chronic illness and immune dysregulation.
This combination is ideal for patients struggling with:
- Autoimmune conditions
- Chronic fatigue or pain
- Multiple food sensitivities
- Cognitive and neurological symptoms
- Mold and chemical exposures
- Gastrointestinal disorders
