Estradiol (E2) Sensitive


This blood test is used to measure Estradiol (E2). Estrogen’s role in supporting health and well-being is as significant as it is diverse. Estradiol is the predominant sex hormone present in women and is also found at lower levels in men. Estradiol not only impacts reproductive and sexual functioning, but also affects mood, attention and language skills.

Evidence is mounting suggesting that estrogen exposure reduces the risk and slows the onset and progression of Alzheimer’s disease. Recent research has documented that estrogen decreases the inflammatory responses associated with dementia and other neurological disorders. The brain protects itself by producing neuroprotective estradiol in response to threatening inflammatory processes that injure brain tissues. Endocrine disruptors such as heavy metals and environmental toxins, processed foods and chronic stress may contribute to an imbalance of the natural production of estrogen. Estradiol is also extremely instrumental in maintaining the integrity of skin, bone, heart and metabolic health. In men, high levels of estradiol are associated with abdominal fat, enlargement of the prostate and cardiovascular risk. For women, when evaluating hormone status, it is important to compare the relationship between estradiol and progesterone. Men should evaluate the relationship between testosterone and estradiol.

Test Preparation For Optimal Results:

If possible, have the lab collected early in the morning or shortly after waking. Do not take supplements on the day of the test. For comparison purposes, have subsequent labs collected close to the same time.

Disclaimer: Your health care provider should evaluate a deviation from normal ranges.