High levels of blood ammonia can harm vital organs, most notably the brain. Ammonia is a waste product that is usually transported to the liver where ammonia is converted to urea through a sequence of reactions known as the urea cycle. One of these processes is the detoxification of ammonia in the blood. When the liver is damaged, the detoxification process is disrupted and ammonia levels can elevate to toxic levels. Elevated levels of ammonia have been found in those who suffer with urinary tract infections and in liver disorders. Because ammonia is one of the most common endogenous (made naturally in the body) neurotoxic compounds, it has been considered to be one of the toxic factors that may contribute to the symptoms and progression of Alzheimer’s disease. Besides neurotoxic effects, elevated ammonia levels may cause confusion, drowsiness, tremors and may induce vomiting.
Test Preparation For Optimal Results:
It is best to be fasting for approximately 9-12 hours prior to lab collection (without food or liquids except water).
Disclaimer: Your health care provider should evaluate a deviation from normal ranges.